Almost all prostate cancers respond to Milk Jug androgen deprivation treatment but many recur.We postulated that risk of hormone escape--frequency and delay--are influenced by hormone therapy modalities.More, hormone therapies induce crucial biological changes involving androgen receptors; some might be targets for escape prevention.We investigated

Abstract Background Treacher Collins syndrome (TCS) is an autosomal dominant craniofacial disorder caused by frameshift deletions or duplications in the TCOF1 gene.These mutations cause premature termination codons, which are predicted to lead to mRNA degradation by nonsense mediated mRNA decay (NMD).Haploinsufficiency of the gene product (treacle)

Objective:Therapeutic management of ductal carcinoma in situ (DCIS) is heterogeneous among countries worldwide, and some treatment indications are still controversial.To investigate DCIS management in different countries; identify both consensual practices and controversial topics; and survey opinions about the future management of DCIS.Materials a

Abstract The purpose of this study was to analyze (1) the influence of organizational culture on positive work behavior; (2) the influence of organizational culture and innovative work behavior on employee performance; and (3) the role of innovative work behavior in mediates the relationship of organizational culture with employee performance.The s

Abstract Simultaneous localization and mapping (SLAM) plays an important role in many fields, one of which is to help unmanned devices such as drones, self-driving cars and intelligent robots to achieve precise positioning and mapping.However, when facing complex or changing surroundings, especially when healthcare robots face a large number of mob